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Innovations of Today

Dr. Vincent Giacalone
Curalta Clinical Trials

Curalta Foot + Ankle brings a wide array of talented practitioners together, but our commitment to excellence and the benefits of shared expertise are only one part of our story. Under the leadership of Dr. Vincent Giacalone, our Director of Research and Clinical Trials, we also make clinical trials and pioneering treatments a top priority.  Advancing medical science is at the heart of delivering exceptional patient care, and we are dedicated to bringing innovative solutions to the forefront. Explore how our cutting-edge clinical trials are redefining healthcare standards and shaping the future of patient care!

Recently Completed  Trials

Diabetic Foot Ulcer with Osteomyelitis

  1. A Phase IIb Randomized, Parallel Group, Double-Blind, Placebo-Controlled, Repeat Dose, Multi-Site Study Investigating the Safety, Tolerability, and Efficacy of Personalized Phage Treatment and Standard of Care Antimicrobials for Patients with Diabetic Foot Osteomyelitis due to S. aureus.
  2. A Multicenter Phase 3 Confirmatory Trial of Biotherapy using Cryopreserved Human Umbilical Cord (TTAX01) for Late Stage, Complex Non- healing Diabetic Foot Ulcers (AMBULATE DFU II).

Diabetic Foot Ulcer - Grade 1 or 2, Non-Infected

 A Multi-Center, Randomized Controlled Clinical Investigation Evaluating Wound Closure with Symphony™ versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers.

Bunionectomy - Post op Pain Study

  1. A Randomized, Double-Blind, Double-Dummy, Parallel-Group, Multi-Center, Active and Placebo- Controlled Trial to Evaluate the Analgesic Efficacy and Safety of NTM-001 (A Novel Formulation of Ketorolac Tromethamine Applied by Continuous Intravenous Infusion from a Pre-Mixed Bag) for the Treatment of Moderately Severe Postoperative Pain Following Bunionectomy.
  2. A Randomized, Double-Blind, Placebo- and Active-Controlled Study to Evaluate the Efficacy and Safety of CPL-01 in the Management of Postoperative Pain After Unilateral Distal First Metatarsal Bunionectomy with Osteotomy.

Venous Leg Ulcer Study

A Prospective, Multicenter, Randomized, Controlled Clinical Study Of Affinity plus Standard of Care (SOC)  compared to SOC alone In The Management Of Venous Leg Ulcers (VLUs).

Plantar Fasciitis

A phase 2, double-blind, randomized, placebo--controlled, dose-ranging study to assess the efficacy, safety, and tolerability of eEN3835 vs placebo in the treatment of recalcitrant plantar fasciitis (PFA).

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